How Does Psilocybin Work?

Psilocybin is a naturally occurring compound found in some wild mushrooms. It is a chemical that offers psychedelic effects when ingested.


Psilocybin, also known as “magic mushrooms” are typically taken orally. Mushrooms can be either dried or fresh and eaten directly as so or brewed in tea.

Effects are typically felt anywhere from 30-60 minutes after ingestion.

Recreational Use

When you think of magic mushrooms, I’m sure your head spins back to the 60’s. You know, the times of tie-die t-shirts and hippies dancing about. While this doesn’t fall too far from the spore; magic mushrooms were certainly a thing of this era and recreational usage of them was as well.

Recreational usage of psilocybin is typically when an individual ingests anywhere from 1.5 grams or more in anticipation of psychedelic effects.

Effects of recreational usage can include:


Increased Creativity

Enhanced Senses

Strong Body High

Mystical Experiences

Sensitivity to Light

Open & Closed Eye Visuals

Altered Time Perception

Medical Microdosing Use

Microdosing psilocybin is quite different than taking recreational doses. When microdosing, hallucinogenic and psychedelic effects should not be felt, but medical benefits can certainly be observed.

A microdose amount is anywhere from .05 grams to 0.25 grams of a psilocybin mushroom.

Some observed effects one may enjoy are:

Mood Enhancement

Decreased Stress & Anxiety

Emotional Stability

Decreased Depression



Increased Focus

Increased Endurance

Psilocybin & The Brain

Prefrontal Cortex

Psilocybin engages the prefrontal cortex of the brain. This portion of the brain participates in what is known as executive functions: personality expression, social behavior, orchestration of thoughts and actions and the planning of cognitive behaviors.

Research has proven that psilocybin as a serotonin receptor causes connections in the brain that would normally be disconnected, ultimately increasing brain activity.

The intercommunication of psilocybin was observed by researchers from Imperial College London.

“These stronger connections are responsible for creating a different state of consciousness.” – Dr. Paul Expert (methodologist and physicist)

Visual Cortex

Psilocybin has been shown to increase activity in the visual cortex which is why taking recreational dosages can distort vision and perception.

Default Mode Network (DMN)

The DMN is a brain network of interacting regions that are scattered throughout the brain that are correlated with one another.

The Default Mode Network (DMN) in the brain is linked to depression and many mood disorders.

Studies have proved that psilocybin has dramatically reduced DMN, ultimately offering itself to fantastic anti-depressant effects.


Psilocybin increases interconnectivity throughout different regions of the brain.

It can be related to an orchestra. Each part of the brain is its own musical instrument and once psilocybin enters, it’s like the conductor arrived to create unity amongst the noise.

Rather than compartmentalized segments, the brain shows dramatic interconnectivity.


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